Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing

Entamoeba histolytica ingests fragments of live host cells in a nibbling-like process termed amebic trogocytosis. Amebic trogocytosis is required for cell killing and contributes to tissue invasion, which is a hallmark of invasive amebic colitis. Work done prior to the discovery of amebic trogocytos...

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Bibliographic Details
Main Authors: Allissia A. Gilmartin, Katherine S. Ralston, William A. Petri, Patricia J. Johnson
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/4/e01187-17