Improved prediction of critical residues for protein function based on network and phylogenetic analyses

<p>Abstract</p> <p>Background</p> <p>Phylogenetic approaches are commonly used to predict which amino acid residues are critical to the function of a given protein. However, such approaches display inherent limitations, such as the requirement for identification of mult...

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Bibliographic Details
Main Authors: Bredesen Dale E, Thibert Boris, del Rio Gabriel
Format: Article
Language:English
Published: BMC 2005-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/6/213