High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression

High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression

High-dose dexamethasone (DEX) is used to treat chemotherapy-induced nausea and vomiting or to control immunotherapy-related autoimmune diseases in clinical practice. However, the underlying mechanisms of high-dose DEX in tumor progression remain unaddressed. Therefore, we explored the effects of hig...

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Bibliographic Details
Main Authors: Lei Xu, Hua Xia, Dongsheng Ni, Yanxia Hu, Jianing Liu, Yao Qin, Qin Zhou, Qiying Yi, Yajun Xie
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
dexamethasone
fao
ffa
glycolysis metabolism
pparα
pparg
tg synthesis
tumor progression
Online Access:https://www.mdpi.com/1422-0067/21/5/1846

Internet

https://www.mdpi.com/1422-0067/21/5/1846

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