Molecular and Pharmacological Characterization of the Interaction between Human Geranylgeranyltransferase Type I and Ras-Related Protein Rap1B

Molecular and Pharmacological Characterization of the Interaction between Human Geranylgeranyltransferase Type I and Ras-Related Protein Rap1B

Geranylgeranyltransferase type-I (GGTase-I) represents an important drug target since it contributes to the function of many proteins that are involved in tumor development and metastasis. This led to the development of GGTase-I inhibitors as anti-cancer drugs blocking the protein function and membr...

Full description

Bibliographic Details
Main Authors: Sonja Hinz, Dominik Jung, Dorota Hauert, Hagen S. Bachmann
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
NanoBiT assay
geranylgeranyltransferase type I
Rap1B
GGTI-298
Adenosine A<sub>2B</sub>- and A<sub>2A</sub>-receptor
Online Access:https://www.mdpi.com/1422-0067/22/5/2501

Internet

https://www.mdpi.com/1422-0067/22/5/2501

Similar Items