Concerted Solvent Processes for Common Sulfonyl Chloride Precursors used in the Synthesis of Sulfonamide-based Drugs

Concerted Solvent Processes for Common Sulfonyl Chloride Precursors used in the Synthesis of Sulfonamide-based Drugs

Specific rates of solvolysis in hydroxylic solvents available for the solvolysis of 2-thiophenesulfonyl chloride and phenylmethanesulfonyl chloride are supplemented by determining the values in fluoroalcohol-containing solvents. The data sets are then correlated using the extended Grunwald-Winstein...

Full description

Bibliographic Details
Main Authors: Dennis N. Kevill, Stacey L. Mlynarski, Lamia Yaakoubd, Malcolm J. D’Souza
Format: Article
Language:English
Published: MDPI AG 2008-05-01
Series:International Journal of Molecular Sciences
Subjects:
solvolysis
sulfonyl transfer
2-thiophenesulfonyl chloride
phenylmethanesulfonyl chloride
Grunwald-Winstein equation.
Online Access:http://www.mdpi.com/1422-0067/9/5/914/

Internet

http://www.mdpi.com/1422-0067/9/5/914/

Similar Items