A double-hit pre-eclampsia model results in sex-specific growth restriction patterns

A double-hit pre-eclampsia model results in sex-specific growth restriction patterns

Pre-eclampsia is a multifactorial pregnancy-associated disorder characterized by angiogenic dysbalance and systemic inflammation; however, animal models that combine these two pathophysiological conditions are missing. Here, we introduce a novel double-hit pre-eclampsia mouse model that mimics the c...

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Bibliographic Details
Main Authors: Violeta Stojanovska, Dorieke J. Dijkstra, Rebekka Vogtmann, Alexandra Gellhaus, Sicco A. Scherjon, Torsten Plösch
Format: Article
Language:English
Published: The Company of Biologists 2019-02-01
Series:Disease Models & Mechanisms
Subjects:
Developmental programming
Metabolomics
Pre-eclampsia
Online Access:http://dmm.biologists.org/content/12/2/dmm035980

Internet

http://dmm.biologists.org/content/12/2/dmm035980

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