Galectin-8 Enhances T cell Response by Promotion of Antigen Internalization and Processing

Summary: Galectin-8 (Gal-8) is a mammalian lectin endowed with immunostimulatory ability. In the present work, we demonstrate that Gal-8-glycan interactions on the surface of antigen-presenting cells (APCs) promote antigen binding and internalization, independently from antigen nature. Both Gal-8 an...

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Bibliographic Details
Main Authors: Cecilia Arahí Prato, Julieta Carabelli, Oscar Campetella, María Virginia Tribulatti
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304648