Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.

Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.

There is much interest in the mechanisms that regulate adult tissue homeostasis and their relationship to processes governing foetal development. Mice deleted for the Wilms' tumour gene, Wt1, lack kidneys, gonads, and spleen and die at mid-gestation due to defective coronary vasculature. Wt1 is...

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Bibliographic Details
Main Authors: You-Ying Chau, David Brownstein, Heidi Mjoseng, Wen-Chin Lee, Natalija Buza-Vidas, Claus Nerlov, Sten Eirik Jacobsen, Paul Perry, Rachel Berry, Anna Thornburn, David Sexton, Nik Morton, Peter Hohenstein, Elisabeth Freyer, Kay Samuel, Rob van't Hof, Nicholas Hastie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3245305?pdf=render

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http://europepmc.org/articles/PMC3245305?pdf=render

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