Mendelian breeding units versus standard sampling strategies: mitochondrial DNA variation in southwest Sardinia

Mendelian breeding units versus standard sampling strategies: mitochondrial DNA variation in southwest Sardinia

We report a sampling strategy based on Mendelian Breeding Units (MBUs), representing an interbreeding group of individuals sharing a common gene pool. The identification of MBUs is crucial for case-control experimental design in association studies. The aim of this work was to evaluate the possible...

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Bibliographic Details
Main Authors: Daria Sanna, Maria Pala, Piero Cossu, Gian Luca Dedola, Sonia Melis, Giovanni Fresu, Laura Morelli, Domenica Obinu, Giancarlo Tonolo, Giannina Secchi, Riccardo Triunfo, Joseph G. Lorenz, Laura Scheinfeldt, Antonio Torroni, Renato Robledo, Paolo Francalacci
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2011-01-01
Series:Genetics and Molecular Biology
Subjects:
breeding units strategy
mtDNA haplogroup distribution
association studies
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000200003

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000200003

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