Docetaxel Skin Exposure and Micronucleation Contributes to Skin Toxicity Caused by CPC634

Docetaxel Skin Exposure and Micronucleation Contributes to Skin Toxicity Caused by CPC634

Docetaxel entrapped nanoparticle CPC634 is associated with dose-related skin toxicity that resembles conventional docetaxel (Cd)-related skin toxicity. This study compared the cutaneous pharmacokinetics and pharmacodynamics of docetaxel and CPC634. In this randomised cross-over study, patients with...

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Bibliographic Details
Main Authors: Florence Atrafi, Ruben A. G. van Eerden, Stijn L. W. Koolen, Peter de Bruijn, Cristianne J. F. Rijcken, Rob Hanssen, Ferry A. L. M. Eskens, Martijn P. Lolkema, Esther Oomen-de Hoop, Jeffrey Damman, Ron H. J. Mathijssen
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
nanoparticles
toxicity
docetaxel
pharmacokinetics
pharmacodynamics
chemotherapy
Online Access:https://www.mdpi.com/2072-6694/13/15/3741

Internet

https://www.mdpi.com/2072-6694/13/15/3741

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