The role of PKR/eIF2α signaling pathway in prognosis of non-small cell lung cancer.

In this study, we investigated whether PKR protein expression is correlated with mRNA levels and also evaluated molecular biomarkers that are associated with PKR, such as phosphorylated PKR (p-PKR) and phosphorylated eIF2α (p-eIF2α).We determined the levels of PKR protein expression and mRNA in 36 f...

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Main Authors: Yong He, Arlene M Correa, Maria Gabriela Raso, Wayne L Hofstetter, Bingliang Fang, Carmen Behrens, Jack A Roth, Yihong Zhou, Liping Yu, Ignacio I Wistuba, Stephen G Swisher, Apar Pataer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3213082?pdf=render