Characterization of a novel population of low-density granulocytes associated with disease severity in HIV-1 infection.

The mechanisms resulting in progressive immune dysfunction during the chronic phase of HIV infection are not fully understood. We have previously shown that arginase, an enzyme with potent immunosuppressive properties, is increased in HIV seropositive (HIV+) patients with low CD4(+) T cell counts. H...

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Bibliographic Details
Main Authors: Thomas Cloke, Markus Munder, Graham Taylor, Ingrid Müller, Pascale Kropf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3496742?pdf=render