Synthesis and Evaluation of the Antibacterial Activities of 13-Substituted Berberine Derivatives

Synthesis and Evaluation of the Antibacterial Activities of 13-Substituted Berberine Derivatives

The biological activities of berberine, a natural plant molecule, are known to be affected by structural modifications, mostly at position 9 and/or 13. A series of new 13-substituted berberine derivatives were synthesized and evaluated in term of antimicrobial activity using various microorganisms a...

Full description

Bibliographic Details
Main Authors: Hamza Olleik, Taher Yacoub, Laurent Hoffer, Senankpon Martial Gnansounou, Kehna Benhaiem-Henry, Cendrine Nicoletti, Malika Mekhalfi, Valérie Pique, Josette Perrier, Akram Hijazi, Elias Baydoun, Josette Raymond, Philippe Piccerelle, Marc Maresca, Maxime Robin
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Antibiotics
Subjects:
berberine derivatives
anti-bacterial agents
microbial sensitivity tests
structure-activity relationship
resistant strain
FtsZ protein
Online Access:https://www.mdpi.com/2079-6382/9/7/381

Internet

https://www.mdpi.com/2079-6382/9/7/381

Similar Items