EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis.

EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis.

Entamoeba histolytica, the highly phagocytic protozoan causative of human amoebiasis lacks the machinery to synthesize cholesterol. Here, we investigated the presence of NPC1 and NPC2 proteins in this parasite, which are involved in cholesterol trafficking in mammals. Bioinformatics analysis reveale...

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Bibliographic Details
Main Authors: Jeni Bolaños, Abigail Betanzos, Rosario Javier-Reyna, Guillermina García-Rivera, Miriam Huerta, Jonnatan Pais-Morales, Arturo González-Robles, Mario A Rodríguez, Michael Schnoor, Esther Orozco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5176366?pdf=render

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http://europepmc.org/articles/PMC5176366?pdf=render

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