Experimental Evidence of A2A–D2 Receptor–Receptor Interactions in the Rat and Human Carotid Body

Experimental Evidence of A2A–D2 Receptor–Receptor Interactions in the Rat and Human Carotid Body

Adenosine A2A receptors (A2AR) and dopamine D2 receptors (D2R) are known to be involved in the physiological response to hypoxia, and their expression/activity may be modulated by chronic sustained or intermittent hypoxia. To date, A2AR and D2R can form transient physical receptor–receptor interacti...

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Bibliographic Details
Main Authors: Elena Stocco, Maria Martina Sfriso, Giulia Borile, Martina Contran, Silvia Barbon, Filippo Romanato, Veronica Macchi, Diego Guidolin, Raffaele De Caro, Andrea Porzionato
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
carotid body
type I cells
adenosine A2A receptors
dopamine D2 receptors
heterodimes
in situ PLA
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.645723/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.645723/full

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