Crystal structure of Diedel, a marker of the immune response of Drosophila melanogaster.

BACKGROUND:The Drosophila melanogaster gene CG11501 is up regulated after a septic injury and was proposed to act as a negative regulator of the JAK/STAT signaling pathway. Diedel, the CG11501 gene product, is a small protein of 115 residues with 10 cysteines. METHODOLOGY/PRINCIPAL FINDINGS:We have...

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Bibliographic Details
Main Authors: Franck Coste, Cordula Kemp, Vanessa Bobezeau, Charles Hetru, Christine Kellenberger, Jean-Luc Imler, Alain Roussel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3307722?pdf=render