Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

Abstract Background The presence of hypoxic areas is common in all breast lesions but no data clearly correlate low oxygenation with the acquisition of malignant features by non-invasive cells, particularly by cells from ductal carcinoma in situ (DCIS), the most frequently diagnosed tumor in women....

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Bibliographic Details
Main Authors: Yasamin Al-Qassab, Silvia Grassilli, Federica Brugnoli, Federica Vezzali, Silvano Capitani, Valeria Bertagnolo
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
DCIS
Hypoxia
Tumor progression
ATRA
PLC-β2
Online Access:http://link.springer.com/article/10.1186/s12885-018-5038-6

Internet

http://link.springer.com/article/10.1186/s12885-018-5038-6

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