Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line
Abstract Background Ovarian cancer is a significant cancer-related cause of death in women worldwide. The most used chemotherapeutic regimen is based on carboplatin (CBDCA). However, CBDCA resistance is the main obstacle to a better prognosis. An in vitro drug-resistant cell model would help in the...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40659-019-0220-0 |