Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis

Limb weakness in amyotrophic lateral sclerosis (ALS) is typically asymmetric. Previous studies have identified an effect of limb dominance on onset and spread of weakness, however relative atrophy of dominant and non-dominant brain regions has not been investigated. Our objective was to use voxel-b...

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Bibliographic Details
Main Authors: Matthew S. Devine, Kerstin Pannek, Alan Coulthard, Pamela A. McCombe, Stephen E. Rose, Robert D. Henderson
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158215000480