Dynamics of linker residues modulate the nucleic acid binding properties of the HIV-1 nucleocapsid protein zinc fingers.

The HIV-1 nucleocapsid protein (NC) is a small basic protein containing two zinc fingers (ZF) separated by a short linker. It is involved in several steps of the replication cycle and acts as a nucleic acid chaperone protein in facilitating nucleic acid strand transfers occurring during reverse tran...

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Bibliographic Details
Main Authors: Loussiné Zargarian, Carine Tisné, Pierre Barraud, Xiaoqian Xu, Nelly Morellet, Brigitte René, Yves Mély, Philippe Fossé, Olivier Mauffret
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25029439/?tool=EBI