Smoking, green tea consumption, genetic polymorphisms in the insulin-like growth factors and lung cancer risk.

Smoking, green tea consumption, genetic polymorphisms in the insulin-like growth factors and lung cancer risk.

Insulin-like growth factors (IGFs) are mediators of growth hormones; they have an influence on cell proliferation and differentiation. In addition, IGF-binding protein (IGFBP)-3 could suppress the mitogenic action of IGFs. Interestingly, tea polyphenols could substantially reduce IGF1 and increase I...

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Main Authors: I-Hsin Lin, Ming-Lin Ho, Hsuan-Yu Chen, Hong-Shen Lee, Chia-Chen Huang, Yin-Hung Chu, Shiau-Yun Lin, Ya-Ru Deng, Yu-Hao He, Yu-Hui Lien, Chi-Wen Hsu, Ruey-Hong Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3274549?pdf=render

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http://europepmc.org/articles/PMC3274549?pdf=render

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