A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid culture

Abstract Bladder cancer is among the most prevalent cancers worldwide. Currently, few bladder cancer models have undergone thorough characterization to assess their fidelity to patient tumors, especially upon propagation in the laboratory. Here, we establish and molecularly characterize CoCaB 1, an...

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Bibliographic Details
Main Authors: Elise Y. Cai, Jose Garcia, Yuzhen Liu, Funda Vakar-Lopez, Sonali Arora, Holly M. Nguyen, Bryce Lakely, Lisha Brown, Alicia Wong, Bruce Montgomery, John K. Lee, Eva Corey, Jonathan L. Wright, Andrew C. Hsieh, Hung-Ming Lam
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83662-7