Involvement of the Intrarenal Renin-Angiotensin System in Experimental Models of Glomerulonephritis

The intrarenal renin-angiotensin system (RAS) has several pathophysiologic functions not only in blood pressure regulation but also in the development of glomerulonephritis (GN). Angiotensin II (Ang II) is the biologically active product of the RAS. Locally produced Ang II induces inflammation, rena...

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Bibliographic Details
Main Authors: Maki Urushihara, Yukiko Kinoshita, Shuji Kondo, Shoji Kagami
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/601786