The interaction between herpes simplex virus 1 genome and promyelocytic leukemia nuclear bodies (PML-NBs) as a hallmark of the entry in latency

The interaction between herpes simplex virus 1 genome and promyelocytic leukemia nuclear bodies (PML-NBs) as a hallmark of the entry in latency

Herpes simplex virus 1 (HSV-1) is a human pathogen that establishes latency in the nucleus of infected neurons in the PNS and the CNS. At the transcriptional level latency is characterized by a quasi-complete silencing of the extrachromosomal viral genome that otherwise expresses more than 80 genes...

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Bibliographic Details
Main Author: Patrick Lomonte
Format: Article
Language:English
Published: Shared Science Publishers OG 2016-11-01
Series:Microbial Cell
Subjects:
Herpesvirus
herpes simplex virus 1 (HSV-1)
latency
neurons
nuclear architecture
promyelocytic leukemia nuclear bodies (PML-NBs)
intrinsic immunity
Online Access:http://microbialcell.com/researcharticles/the-interaction-between-herpes-simplex-virus-1-genome-and-promyelocytic-leukemia-nuclear-bodies-pml-nbs-as-a-hallmark-of-the-entry-in-latency/

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http://microbialcell.com/researcharticles/the-interaction-between-herpes-simplex-virus-1-genome-and-promyelocytic-leukemia-nuclear-bodies-pml-nbs-as-a-hallmark-of-the-entry-in-latency/

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