Vaccination with human papillomavirus pseudovirus-encapsidated plasmids targeted to skin using microneedles.

Vaccination with human papillomavirus pseudovirus-encapsidated plasmids targeted to skin using microneedles.

Human papilloma virus-like particles (HPV VLP) serve as the basis of the current licensed vaccines for HPV. We have previously shown that encapsidation of DNA expressing the model antigen M/M2 from respiratory syncytial virus (RSV) in HPV pseudovirions (PsV) is immunogenic when delivered intravagina...

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Bibliographic Details
Main Authors: Rhonda C Kines, Vladimir Zarnitsyn, Teresa R Johnson, Yuk-Ying S Pang, Kizzmekia S Corbett, John D Nicewonger, Anu Gangopadhyay, Man Chen, Jie Liu, Mark R Prausnitz, John T Schiller, Barney S Graham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364728?pdf=render

Internet

http://europepmc.org/articles/PMC4364728?pdf=render

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