EspFu-Mediated Actin Assembly Enhances Enteropathogenic Escherichia coli Adherence and Activates Host Cell Inflammatory Signaling Pathways
EPEC is among the leading causes of diarrheal disease worldwide. The colonization of the gut mucosa by EPEC results in actin pedestal formation at the site of bacterial attachment. These pedestals are referred to as attaching and effacing (AE) lesions. Here, we exploit the different molecular mechan...
Main Authors: | Fernando H. Martins, Ashwani Kumar, Cecilia M. Abe, Eneas Carvalho, Milton Nishiyama-Jr, Chao Xing, Vanessa Sperandio, Waldir P. Elias |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-04-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.00617-20 |
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