Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety

Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor cell lines. In our previous study, the combination of thiourea and phosphonate has been proven as an effective strategy for developing antitumor agents. Herein, we synthesized and evaluated a series o...

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Bibliographic Details
Main Authors: Jingzi Liu, Peng Liao, Junfeng Hu, Hong Zhu, Yonglin Wang, Yongjun Li, Yan Li, Bin He
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/2/238