Management of Hereditary Spastic Paraplegia: A Systematic Review of the Literature

The term hereditary spastic paraplegia (HSP) embraces a clinically and genetically heterogeneous group of neurodegenerative diseases characterized by progressive spasticity and weakness of the lower limbs. There currently exist no specific therapies for HSP, and treatment is exclusively symptomatic,...

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Bibliographic Details
Main Authors: Marta Bellofatto, Giovanna De Michele, Aniello Iovino, Alessandro Filla, Filippo M. Santorelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00003/full