CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer.

The cyclin-dependent kinase inhibitor 3 (CDKN3) gene, involved in mitosis, is upregulated in cervical cancer (CC). We investigated CDKN3 mRNA as a survival biomarker and potential therapeutic target for CC. CDKN3 mRNA was measured in 134 CC and 25 controls by quantitative PCR. A 5-year survival stud...

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Bibliographic Details
Main Authors: Eira Valeria Barrón, Edgar Roman-Bassaure, Ana Laura Sánchez-Sandoval, Ana María Espinosa, Mariano Guardado-Estrada, Ingrid Medina, Eligia Juárez, Ana Alfaro, Miriam Bermúdez, Rubén Zamora, Carlos García-Ruiz, Juan Carlos Gomora, Susana Kofman, E Martha Pérez-Armendariz, Jaime Berumen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4570808?pdf=render