Diversity of natural self-derived ligands presented by different HLA class I molecules in transporter antigen processing-deficient cells.

Diversity of natural self-derived ligands presented by different HLA class I molecules in transporter antigen processing-deficient cells.

The transporter associated with antigen processing (TAP) translocates the cytosol-derived proteolytic peptides to the endoplasmic reticulum lumen where they complex with nascent human leukocyte antigen (HLA) class I molecules. Non-functional TAP complexes and viral or tumoral blocking of these trans...

Full description

Bibliographic Details
Main Authors: Elena Lorente, Susana Infantes, Eilon Barnea, Ilan Beer, Alejandro Barriga, Noel García-Medel, Fátima Lasala, Mercedes Jiménez, Arie Admon, Daniel López
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608615?pdf=render

Internet

http://europepmc.org/articles/PMC3608615?pdf=render

Similar Items