Early life stress induces dysregulation of the heme pathway in adult mice

Abstract Early life stress (ELS) is associated with cardiovascular disease (CVD) risk in adulthood, but the underlying vascular mechanisms are poorly understood. Increased hemoglobin and heme have recently been implicated to mediate endothelial dysfunction in several vascular diseases. Chronic physi...

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Bibliographic Details
Main Authors: Yasminye D. Pettway, Thomas H. Neder, Dao H. Ho, Brandon M. Fox, Mariah Burch, Jackson Colson, Xiaofen Liu, Cailin E. Kellum, Kelly A. Hyndman, Jennifer S. Pollock
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14844