The effects of CRISPR-Cas9 knockout of the TGF-β1 gene on antler cartilage cells in vitro

Abstract Background Deer antler is the only mammalian organ that can be completely regenerated every year. Its periodic regeneration is regulated by multiple factors, including transforming growth factor β (TGF-β). This widely distributed multi-functional growth factor can control the proliferation...

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Bibliographic Details
Main Authors: Mingxiao Liu, Xiangyu Han, Hongyun Liu, Danyang Chen, Yue Li, Wei Hu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11658-019-0171-z