Comprehensive DNA Methylation Analysis of Retrotransposons in Male Germ Cells

De novo DNA methylation of retrotransposons is critical for silencing. Here, we use DNA methylation analysis to examine retrotransposons in mouse male germ cells. DNA methylation of long interspersed nuclear elements (LINEs) is dependent on piRNA, and younger LINEs exhibit greater piRNA dependence....

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Bibliographic Details
Main Authors: Ippei Nagamori, Hisato Kobayashi, Yusuke Shiromoto, Toru Nishimura, Satomi Kuramochi-Miyagawa, Tomohiro Kono, Toru Nakano
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715008505