The use of pulse pressure variation for predicting impairment of microcirculatory blood flow

Abstract Dynamic parameters of preload have been widely recommended to guide fluid therapy based on the principle of fluid responsiveness and with regard to cardiac output. An equally important aspect is however to also avoid volume-overload. This accounts particularly when capillary leakage is pres...

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Bibliographic Details
Main Authors: Christoph R. Behem, Michael F. Graessler, Till Friedheim, Rahel Kluttig, Hans O. Pinnschmidt, Anna Duprée, E. Sebastian Debus, Daniel A. Reuter, Sabine H. Wipper, Constantin J. C. Trepte
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88458-3