GM-CSF enhanced the effect of CHOP and R-CHOP on inhibiting diffuse large B-cell lymphoma progression via influencing the macrophage polarization

GM-CSF enhanced the effect of CHOP and R-CHOP on inhibiting diffuse large B-cell lymphoma progression via influencing the macrophage polarization

Abstract Background Diffuse large B-cell lymphoma (DLBCL) is a common type of the Non-Hodgkin lymphomas (NHLs) formed by the neoplastic transformation of mature B cells. As the first-line therapeutics, CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) chemotherapy and R-CHOP (Rituximab + CH...

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Bibliographic Details
Main Authors: Yu Zhang, Jingjing Xiang, Xianfu Sheng, Ni Zhu, Shu Deng, Junfa Chen, Lihong Yu, Yan Zhou, Chenjun Lin, Jianping Shen
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cancer Cell International
Subjects:
GM-CSF
CHOP
R-CHOP
Diffuse large B-cell lymphoma
Tumor microenvironment
Macrophage
Online Access:https://doi.org/10.1186/s12935-021-01838-7

Internet

https://doi.org/10.1186/s12935-021-01838-7

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