Novel loci for non-syndromic coarctation of the aorta in sporadic and familial cases.

BACKGROUND:Coarctation of the aorta (CoA) accounts for 5-8% of all congenital heart defects. CoA can be detected in up to 20% of patients with Ullrich-Turner syndrome (UTS), in which a part or all of one of the X chromosomes is absent. The etiology of non-syndromic CoA is poorly understood. In the p...

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Bibliographic Details
Main Authors: Julia Moosmann, Steffen Uebe, Sven Dittrich, André Rüffer, Arif B Ekici, Okan Toka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4436177?pdf=render