The secretome of adipose-derived mesenchymal stem cells attenuates epithelial–mesenchymal transition in human corneal epithelium

Introduction: Epithelial–mesenchymal transition (EMT) induces the loss of cell–cell interactions in polarized epithelial cells and converts these cells to invasive mesenchymal-like cells. It is also involved in tissue fibrosis including that occurring in some ocular surface diseases such as pterygiu...

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Bibliographic Details
Main Authors: Shun Shibata, Ryuhei Hayashi, Toru Okubo, Yuji Kudo, Koichi Baba, Yoichi Honma, Kohji Nishida
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320419300422