An Injectable Hydrogel for Enhanced FeGA-Based Chemodynamic Therapy by Increasing Intracellular Acidity

An Injectable Hydrogel for Enhanced FeGA-Based Chemodynamic Therapy by Increasing Intracellular Acidity

Hydroxyl radical (•OH)-mediated chemodynamic therapy (CDT) is an emerging antitumor strategy, however, acid deficiency in the tumor microenvironment (TME) hampers its efficacy. In this study, a new injectable hydrogel was developed as an acid-enhanced CDT system (AES) for improving tumor therapy. Th...

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Bibliographic Details
Main Authors: Wen Zeng, Dazhen Jiang, Zeming Liu, Weilong Suo, Ziqi Wang, Daoming Zhu, Qinqin Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
FeGA
hydrogel
α-CHCA
chemodynamic therapy and tumor therapy
intracellular acidity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.750855/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.750855/full

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