Systematic Study of the Physicochemical Properties of a Homologous Series of Aminobisphosphonates

Systematic Study of the Physicochemical Properties of a Homologous Series of Aminobisphosphonates

Aminobisphosphonates, e.g., alendronate and neridronate, are a well known class of molecules used as drugs for various bone diseases. Although these molecules have been available for decades, a detailed understanding of their most important physicochemical properties under comparable conditions is l...

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Bibliographic Details
Main Authors: Jouko Vepsäläinen, Sirpa Peräniemi, Erkki Kolehmainen, Petri Turhanen, Manu Lahtinen, Markku Ylisirniö, Helena Hyvönen, Aino-Liisa Alanne
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Molecules
Subjects:
bisphosphonates
aqueous solubility
pKa
physicochemical properties
Online Access:http://www.mdpi.com/1420-3049/17/9/10928

Internet

http://www.mdpi.com/1420-3049/17/9/10928

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