TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells

TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells

The relative potency and quality of mouse B cell response to Toll-like receptors (TLRs) signaling varies significantly depending on the B cell subset and on the TLR member being engaged. Although it has been shown that marginal zone cells respond faster than follicular (FO) splenic B cells to TLR4 s...

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Bibliographic Details
Main Authors: Bárbara José Antunes Baptista, Alessandra Granato, Fábio B. Canto, Fabricio Montalvão, Lucas Tostes, Herbert L. de Matos Guedes, Antonio Coutinho, Maria Bellio, Andre M. Vale, Alberto Nobrega
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
follicular B cell
plasma cell
TLR9
TLR4
limiting dilution
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02281/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02281/full

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