Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents

In connection with our research program on the development of novel indolin-2-one-based anticancer candidates, herein we report the design and synthesis of different series of hydrazonoindolin-2-ones 3a-e, 5a-e, 7a-c, and 10a-l. The synthesised derivatives were in vitro evaluated for their anti-prol...

Full description

Bibliographic Details
Main Authors: Wagdy M. Eldehna, Reem I. Al-Wabli, Maha S. Almutairi, Adam B. Keeton, Gary A. Piazza, Hatem A. Abdel-Aziz, Mohamed I. Attia
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:http://dx.doi.org/10.1080/14756366.2018.1462802