Development of a large animal model of lethal polytrauma and intra-abdominal sepsis with bacteremia

Background Trauma and sepsis are individually two of the leading causes of death worldwide. When combined, the mortality is greater than 50%. Thus, it is imperative to have a reproducible and reliable animal model to study the effects of polytrauma and sepsis and test novel treatment options. Porcin...

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Bibliographic Details
Main Authors: Umar F Bhatti, Yongqing Li, Rachel L O'Connell, Ali Siddiqui, Nathan Graham, Kiril Chtraklin, Alizeh Shamshad
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:Trauma Surgery & Acute Care Open
Online Access:https://tsaco.bmj.com/content/6/1/e000636.full