Heme Oxygenase-1 as a Pharmacological Target for Host-Directed Therapy to Limit Tuberculosis Associated Immunopathology

Excessive inflammation and tissue damage are pathological hallmarks of chronic pulmonary tuberculosis (TB). Despite decades of research, host regulation of these clinical consequences is poorly understood. A sustained effort has been made to understand the contribution of heme oxygenase-1 (HO-1) to...

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Bibliographic Details
Main Authors: Krishna C. Chinta, Hayden T. Pacl, Anupam Agarwal, Adrie J. C. Steyn
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Antioxidants
Subjects:
TB
Online Access:https://www.mdpi.com/2076-3921/10/2/177