Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo.

Neutrophils and macrophages provide the first line of cellular defence against pathogens once physical barriers are breached, but can play very different roles for each specific pathogen. This is particularly so for fungal pathogens, which can occupy several niches in the host. We developed an infec...

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Bibliographic Details
Main Authors: Felix Ellett, Vahid Pazhakh, Luke Pase, Erica L Benard, Harshini Weerasinghe, Denis Azabdaftari, Sultan Alasmari, Alex Andrianopoulos, Graham J Lieschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6010348?pdf=render