Transient inhibition and long-term facilitation of locomotion by phasic optogenetic activation of serotonin neurons

Transient inhibition and long-term facilitation of locomotion by phasic optogenetic activation of serotonin neurons

Serotonin (5-HT) is associated with mood and motivation but the function of endogenous 5-HT remains controversial. Here, we studied the impact of phasic optogenetic activation of 5-HT neurons in mice over time scales from seconds to weeks. We found that activating dorsal raphe nucleus (DRN) 5-HT neu...

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Bibliographic Details
Main Authors: Patrícia A Correia, Eran Lottem, Dhruba Banerjee, Ana S Machado, Megan R Carey, Zachary F Mainen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
serotonin
dorsal raphe nucleus
locomotion
optogenetics
Online Access:https://elifesciences.org/articles/20975

Internet

https://elifesciences.org/articles/20975

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