High circulating elafin levels are associated with Crohn's disease-associated intestinal strictures.

BACKGROUND:Antimicrobial peptide expression is associated with disease activity in inflammatory bowel disease (IBD) patients. IBD patients have abnormal expression of elafin, a human elastase-specific protease inhibitor and antimicrobial peptide. We determined elafin expression in blood, intestine,...

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Bibliographic Details
Main Authors: Jiani Wang, Christina Ortiz, Lindsey Fontenot, Ying Xie, Wendy Ho, S Anjani Mattai, David Q Shih, Hon Wai Koon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231796