Comparing Proteolytic Fingerprints of Antigen-Presenting Cells during Allergen Processing

Comparing Proteolytic Fingerprints of Antigen-Presenting Cells during Allergen Processing

Endolysosomal processing has a critical influence on immunogenicity as well as immune polarization of protein antigens. In industrialized countries, allergies affect around 25% of the population. For the rational design of protein-based allergy therapeutics for immunotherapy, a good knowledge of T c...

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Bibliographic Details
Main Authors: Heidi Hofer, Tamara Weidinger, Peter Briza, Claudia Asam, Martin Wolf, Teresa E. Twaroch, Frank Stolz, Angela Neubauer, Elfriede Dall, Peter Hammerl, Alain Jacquet, Michael Wallner
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:International Journal of Molecular Sciences
Subjects:
allergen proteolysis
Bet v 1
Amb a 1
Der p 1
Der p 2
proteases from dendritic cells
proteases from macrophages
proteases from B cells
degradome assay
Online Access:http://www.mdpi.com/1422-0067/18/6/1225

Internet

http://www.mdpi.com/1422-0067/18/6/1225

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