In vitro therapy against glioblastoma cells by 3-Dezaneplanocin-A, panobinostat, and temozolomide

In vitro therapy against glioblastoma cells by 3-Dezaneplanocin-A, panobinostat, and temozolomide

Background: Glioblastoma multiforme (GBM) is the most malignant primary brain tumor. Current treatment against this tumor consists of maximal surgical resection without threatening the patient's life, followed by a treatment with temozolomide, with or without combined radiotherapy. GBM is resis...

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Bibliographic Details
Main Authors: Javier de la Rosa, Alejandro Urdiciain, Bárbara Meléndez, Juan A Rey, Miguel A Idoate, Javier S Castresana
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Glioma
Subjects:
Brain tumors
epigenetics
EZH2
histone deacetylase
histone methylase
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2018;volume=1;issue=1;spage=22;epage=26;aulast=de

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http://www.jglioma.com/article.asp?issn=2589-6113;year=2018;volume=1;issue=1;spage=22;epage=26;aulast=de

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