Role of sodium‐dependent Pi transporter/Npt2c on Pi homeostasis in klotho knockout mice different properties between juvenile and adult stages

Role of sodium‐dependent Pi transporter/Npt2c on Pi homeostasis in klotho knockout mice different properties between juvenile and adult stages

Abstract SLC34A3/NPT2c/NaPi‐2c/Npt2c is a growth‐related NaPi cotransporter that mediates the uptake of renal sodium‐dependent phosphate (Pi). Mutation of human NPT2c causes hereditary hypophosphatemic rickets with hypercalciuria. Mice with Npt2c knockout, however, exhibit normal Pi metabolism. To i...

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Bibliographic Details
Main Authors: Ai Hanazaki, Kayo Ikuta, Shohei Sasaki, Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Yuki Arima, Ichiro Kaneko, Yuji Shiozaki, Sawako Tatsumi, Tomoka Hasegawa, Norio Amizuka, Ken‐ichi Miyamoto, Hiroko Segawa
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Physiological Reports
Subjects:
FGF23/klotho
growth
intestine
kidney
phosphate transporter
Online Access:https://doi.org/10.14814/phy2.14324

Internet

https://doi.org/10.14814/phy2.14324

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