Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

Abstract This study aimed to determine the pattern of [18F]flortaucipir uptake in individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the PRNP F198S mutation. The aims were to: 1) determine the pattern of [18F]flortaucipir uptake in two GSS patients; 2) compare tau d...

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Bibliographic Details
Main Authors: Shannon L. Risacher, Martin R. Farlow, Daniel R. Bateman, Francine Epperson, Eileen F. Tallman, Rose Richardson, Jill R. Murrell, Frederick W. Unverzagt, Liana G. Apostolova, Jose M. Bonnin, Bernardino Ghetti, Andrew J. Saykin
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Acta Neuropathologica Communications
Subjects:
Positron emission tomography (PET)
[18F]flortaucipir/AV-1451/T-807
Gerstmann-Sträussler-Scheinker disease (GSS)
Tau
Prion protein (PrP)
PRNP F198S mutation
Online Access:http://link.springer.com/article/10.1186/s40478-018-0608-z

Internet

http://link.springer.com/article/10.1186/s40478-018-0608-z

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